Heart & Circulatory System
Astonin® Merck tablet
Chemical:
* Fludrocortisone
Manufacturer: Merck Farma y Quimica S.L.
40 pieces
How does the ingredient?
The fludrocortisone has been approved to replace missing hormones in loss of hormone production in the adrenal glands (eg for Addison's disease or syndrome androgenitalen and short-term treatment of low blood pressure.
The Addison's disease is caused by decreased or absent hormone production in the adrenal cortex. Typical symptoms include fatigue, general exhaustion, weight loss, a dark discoloration of the skin, low blood pressure with a tendency to collapse conditions, and gastrointestinal complaints.
A large group of inborn errors of metabolism of the adrenal glands is summarized under the term androgenitales syndrome. In most subtypes creates a lack of cortisone and aldosterone, while an overproduction of male sex hormones called androgens.
Girl with androgenitalem syndrome at birth, already show a visible masculinization of their external sexual organs, while boys often only a premature onset of puberty is noted. While there is also loss of salt by the kidney disease, are already appearing in the second or third week of life in newborns of both sexes serious disturbances in the regulation of mineral balance. These children have their whole lives taking adrenal hormones in tablet form.
Fludrocortisone is a synthetic hormone from the adrenal cortex (mineralocorticoid). It prevents the kidney in the excretion of salt and water, whereby the blood volume - and thus the blood pressure - rise. In addition, improved circulation in small blood vessels.
Applications
* Addison's disease
* Androgenitales syndrome with salt loss through the kidneys
* Short-term therapy of severe low blood pressure requiring treatment
Warnings
None!
When the drug is not) suitable for you (if I overdose?
* Hypersensitivity to fludrocortisone, or any other component of the product, it should not be taken.
* For all diseases associated with an increased accumulation of Bindegewebswasser (edema), such as heart failure, persistent renal dysfunction or liver cirrhosis;
* High blood pressure (hypertension);
* Low Bludruck due to a lack of volume or circulatory shock;
* Potassium deficiency (hypokalemia);
* Advanced atherosclerosis of brain vessels with loss of mental capacity;
Pregnancy and Lactation
* During pregnancy, the doctor must perform adjust the dose of the drug (increase), and frequent checks of blood pressure and blood minerals. Chronically low blood pressure is just one of the reasons for using the drug, it should - especially in the first three months of pregnancy - a careful risk-benefit assessment by the kind of place.
* Breast feeding the drug should not be used if possible, unless your doctor believes this is essential.
Effects
Sometimes people are allergic to medication. If you have any signs of an allergic reaction, immediately contact your doctor or pharmacist.
Here are listed the most important known side effects. They can occur, but need not, as each person responds differently to medications.
* Weight gain
* Gewebsödeme
* Hypertension
* Potassium deficiency
* Headache
Interaction
Drugs that may increase a potassium deficiency are: water resources of the type of driving saluretics, digitalis, and laxatives.
Glycyrrhizinhaltige for the treatment of gastrointestinal ulcers and non-steroidal anti-Rheumatika (NSAIDs) increase the effect of fludrocortisone and may enhance edema, potassium deficiency and hypertension.
The drug can amplify its own initiative or to reduce the effect of other drugs. Keep always consult with their doctor or pharmacist if you are taking other medications.
This text makes no claim to completeness. We list only clinically significant information. The description is neutral and based on the Federal Institute for Drugs and Medical Devices (BfArM) recognized specialized information. The information does not endorse or promote the preparation dar. you do not replace the advice of a doctor or pharmacist.