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Urbason 16 mg Methylprednisolone

26,95 EUR
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Product No.: 863167.4
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Urbason 16 mg Methylprednisolone
Urbason 16 mg Methylprednisolone

Urbason 16 mg tablets

Chemical:
• Methylprednisolone

Manufacturer: Sanofi-Aventis

30 tablets

How does the component?

Methylprednisolone is a synthetic glucocorticoid and affects the metabolism of most tissues. This regulates the body's response to methylprednisolone rest and stress situations, and controls the activity of the immune system.

Applications

• Asthma
• obstructive airway diseases
• Interstitial lung disease
• pollinosis
• Allergic rhinitis
• Severe skin and mucosal diseases
• Autoimmune diseases
• Rheumatoid arthritis
• Juvenile arthritis
• hemolytic anemia
• Ulcerative colitis
• Crohn's Disease
• Addison's disease
• Congenital adrenogenital syndrome.

Warning!

• The drug should be used only 8 weeks before and up to 2 weeks after vaccination, if your doctor considers it imperative
• If possible infections should be carried out in parallel a therapy against the pathogen
• medicines for chronic diseases such as diabetes, heart failure and high blood pressure have to be dosed again also by your doctor.

When the drug is not suitable for you (dialysis)

It is not suitable for a known hypersensitivity to any ingredient. For short-term use, there are no other contraindications. Contraindications for a longer-term use are:

• gastrointestinal ulcers
• Severe osteoporosis
• Psychiatric problems
• Acute viral infections (herpes zoster, herpes simplex, chicken pox)
• HBsAg-positive chronic active hepatitis
• Systemic fungal infections and parasitic diseases, poliomyelitis, lymphadenitis after BCG vaccination, and wide-angle glaucoma Eng
• For existing infections and diseases such as diabetes, high blood pressure and certain intestinal problems, a careful risk-benefit assessment done
• growing children and the elderly should be used only in urgent cases.

Pregnancy and Lactation

• During pregnancy, especially in the first three months, the drug should only be used if your doctor considers it absolutely necessary. Keep Therefore, before use of the drug talking to your doctor
• For long-term treatment include growth disorders in children in the womb can not be excluded
• For a treatment to the end of pregnancy there is a child's risk of tissue atrophy of the adrenal cortex
• During lactation the drug passes into breast milk. If treatment requires higher doses or a long term treatment should be discontinued.

Side effects

Listed are the most important known side effects. They can occur, but need not, because each person responds differently to medications.
Sometimes people are allergic to medication. If you experience symptoms of an allergic reaction, tell your doctor or pharmacist.
The risk of side effects is low in short-term methylprednisolone treatment, an exception is the high-dose therapy, are also expected in the short-term administration with infected. Side effects occur, however, especially during long-term treatment with prednisone:

• Full moon face, truncal obesity
• menstrual disorders, impotence
• Male hair growth in women
• Adrenal suppression
• Diabetes mellitus
• edema
• Increased potassium excretion
• Skin disorders: stria rubra, atrophy, petechiae, bruising, steroid acne, delayed wound healing, perioral dermatitis
• muscle wasting, osteoporosis, necrosis of bone parts
• depression, irritability, euphoria, increased appetite and drive, pseudotumor cerebri epilepsy,
• gastrointestinal ulcers, gastrointestinal bleeding, pancreatitis
• hypertension, atherosclerosis and increase the risk of thrombosis, inflammation of the veins and arteries
• Slightly increased production of white blood cells, lymphopenia, eosinopenia, polycythemia, weakening the immune system, masking of infections
• Glaucoma, cataract
• Muscle and joint pain (with rapid discontinuation of the drug)
• Growth retardation in children.


Interaction

With additional application of the following drugs the side effects can be enhanced or the drug effect can be changed:

• Nonsteroidal anti-inflammatory drugs: increased risk of bleeding and ulcers in the gastrointestinal tract
• Oral hypoglycaemic agents and insulin, blood sugar levels is reduced
• Certain antibiotics such as rifampicin and barbiturates, phenytoin and primidone, antacids: methylprednisolone reduce the effect
• Oral anticoagulants: are weakened in their effect
• estrogen-containing contraceptives (the pill) enhances the effect of methylprednisolone-
• atropine and other anticholinergics: additional intraocular pressure increase possible
• Non-depolarizing muscle relaxants: the muscle may last longer
• cardiac glycosides (eg digitalis): Additional impact of possible potassium deficiency
• Praziquantel: Drop of the blood concentration of possible
• ACE inhibitors: Increased risk of blood disorders
• chloroquine, hydroxychloroquine, mefloquine: Increased risk of occurrence of myopathies and cardiomyopathies
• Somatropin: effect can be reduced
• protirelin: TSH rise may be reduced
• Cyclosporine: increased blood levels, increased risk of epileptic seizures
• Theophylline: excretion can be influenced (increased in adults, delayed in children).

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